Jayant Pinto

My research program focuses on identifying risk factors for and consequences of age-related disorders in humans, understanding the underlying mechanisms, and testing clinical interventions that prevent, mitigate, and reverse the resultant burdens.

This work examines biodemographic, environmental, social, and genetic factors in several large cohorts of older adults, including the Rush Memory and Aging Project (MAP) and the National Social Life, Health, and Aging Project (NSHAP). I have also performed studies in the Chronic Rhinosinusitis Integrated Studies Program (CRISP) examining genetic and epigenetic influences on inflammatory airway disease as part of the Toxicant Exposures and Responses by Genomic and Epigenomic Regulators of Transcription (Target) II consortium.

I currently lead as co-PI the Air Pollution & Alzheimer’s Dementia: Neuropathologic & Olfactory Mechanisms in Multi-Ethnic Longitudinal Cohorts study (AERONOSE) which examines the effects of PM exposure on olfaction and cognition.

In summary, I am very interested in understanding how changes in the environment affect human disease and behavior in a population health context.